Additionally, it was determined that there was a possibility the observed retinal abnormalities were not caused by acute hyperglycemia but rather the loss of IGF-1 activity in cases of diabetes [4]
This makes it a powerful tool for individuals struggling with high blood sugar and weight management
doi:10.1016/S0140-6736(24)00194-3 Marso SP, Bain SC, Consoli A, et al
But theres no evidence that this causes substantial weight loss. The gastrointestinal side effects of GLP-1 agonists are well documented, and GLP-1 boosting supplements draw consumers in by bragging about their lack of side effects
1: Sikiric P, Barisic I, Udovicic M, Lovric Bencic M, Balenovic D, Strinic D, Posilovic GZ, Uzun S, Vranes H, Krezic I, Lozic M, Stambolija V, Premuzic Mestrovic I, Oreskovic LB, Kalogjera L, Strbe S, Sikiric S, Tomic L, Stupnisek M, Kordic M, Tvrdeic A, Seiwerth S, Boban Blagaic A, Skrtic A
Patients treated with semaglutide commonly experience weight reductions averaging 10% to 15% of their total body weight, significantly outperforming the 5% to 7% reduction typically seen with liraglutide