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Excess iron catalyzes the aggregation and hyperphosphorylation of -amyloid and tau proteins, which are the major pathologies of AD, contributing to senile plaques and neurofibrillary tangles (Levi et al., 2024)
Iron is also found in the brain, providing conditions conductive to ferroptosis in Wilson disease
Additionally, western blot analysis revealed reduced expression of ACSL4 and TFR1 (Fig
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Free Radic Biol Med 2013
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