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Clinical studies have consistently shown that retatrutide, when used as an adjunct therapy to existing diabetes medications, significantly lowers HbA1c levelsa critical marker of long-term blood sugar control

What they're saying: "People with obesity and knee osteoarthritis often live with pain and restricted mobility, and may eventually require total joint replacement," Kenneth Custer, executive vice president and president of Lilly Cardiometabolic Health, said in a statement

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Both medications showed no increased serious adverse events in seniors, though nausea and vomiting rates were slightly higher (28% vs 24% for tirzepatide)