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Results Interim analysis The trial was halted early in October 2023 after the DSMB performed an interim analysis after 570 events had accrued, and stopping rules were met
Influence of gene polymorphisms on vitiligo patients Several gene polymorphisms have been considered potential risk factors in the development of vitiligo, regardless of the type of disease (chemical-induced or idiopathic) in the search of an association between genotype and symptom
Early concerns about pancreatitis (inflammation of the pancreas) led to close monitoring
Overuse and Toxicity Excessive intake of L-carnitine can lead to toxicity, which can result in side effects such as dizziness, muscle weakness, and nausea
8 Cost The high cost of these medications is a barrier to many patients continuing them, with US list prices or $12,000-16,000 per year, and over $6500 a year at maximum discount