A randomized controlled trial of dietary improvement for adults with major depression (the SMILES trial)
However, long-term trials are necessary to conclude the clinical safety of this peptide
Annals of the New York Academy of Sciences (2010) Crockford D Annals of the New York Academy of Sciences (2007)

The Acute Impact of a Single Taurine Dose on Exercise Performance: A Meta-Analytic Review The Effect of Taurine on the Recovery from Eccentric Exercise-Induced Muscle Damage in Males Taurine supplementation reduces eccentric exercise-induced delayed onset muscle soreness in young men Taurine: the appeal of a safe amino acid for skeletal muscle disorders Taurine in sports and exercise Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise Taurine as a Natural Antioxidant: From Direct Antioxidant Effects to Protective Action in Various Toxicological Models The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis Taurine, caffeine, and energy drinks: Reviewing the risks to the adolescent brain Effects of L-carnitine supplementation on markers of exercise-induced muscle damage in healthy adults: A systematic review and meta-analysis of randomized controlled trials Effects of nine weeks L-Carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress in resistance-trained males Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial Effects of L-Carnitine Intake on Exercise-Induced Muscle Damage and Oxidative Stress: A Narrative Scoping Review The Effect of Two-Week L-Carnitine Supplementation on Exercise -Induced Oxidative Stress and Muscle Damage Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update Androgenic responses to resistance exercise: effects of feeding and L-carnitine Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance trained males Effectiveness of Propionyl-L-Carnitine Supplementation on Exercise Performance in Intermittent Claudication: A Systematic Review Carnitine Fact Sheet for Health Professionals L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis Efficacy and Safety of L-Carnitine Treatment for Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomized controlled trial Can Magnesium Enhance Exercise Performance

While appealing for rapid weight cuts in weight-class sports, semaglutide can compromise long-term performance and health if used as a shortcut rather than part of a structured plan
Research-grade retatrutide is the efficacy frontier, the newest mechanism and the largest trial effect, the compound to study when the question is about maximal response