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In the presence of VEGF, MDSCs can create a pro-angiogenic milieu within the tumors by secreting angiogenic factors including CCL2, CXCL8, CXCL2, IL-1, ANGPT1, ANGPT2, and GM-CSF [251, 252]
A., El-readi, M
No lethal dose was identified across a wide dose range from 0.006 mg/kg to 20 mg/kg body weight
doi: 10.1016/j.cofs.2019.03.005 2
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