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Additionally, RXFP1 couples with G subunits to activate phosphoinositide 3-kinase (PI3K), which in turn phosphorylates protein kinase B (PKB/Akt), promoting endothelial nitric oxide synthase-mediated nitric oxide production and subsequent vasodilation

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GSIS, glucose-stimulated insulin secretion

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Systemic side effects from topical minoxidil are uncommon but possible

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muciniphila has garnered significant attention as a therapeutic target for metabolic syndrome (439)

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Though only Wegovy is also approved as a weight loss medication, other drugs have been used off-label for weight loss

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