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"It is unclear if [the data] is specific to one of the GLP-1 drugs, if it relates to a specific headache type, or if there are safety and tolerability concerns to watch for," said Jessica Ailani, MD, a professor of clinical neurology and director of the Georgetown Headache Center at MedStar Georgetown University Hospital
April 9, 2026
Rosenstock J, Allison D, Birkenfeld AL et al (2019) Effect of additional oral semaglutide vs sitagliptin on glycated hemoglobin in adults with type 2 diabetes uncontrolled with metformin alone or with sulfonylurea: the PIONEER 3 randomized clinical trial
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Less common but serious side effects can include pancreatitis, gallbladder disease, kidney issues, or changes in vision
