Who should not take GLP-1 drugs for cosmetic weight loss
Gattrell WT, Logullo P, van Zuuren EJ, Price A, Hughes EL, Blazey P, et al
Whilst this may seem beneficial for patients with obesity, excessive or rapid weight loss can lead to nutritional deficiencies, muscle wasting, gallstone formation, and metabolic disturbances
The sudden shift in appetite and eating patterns changes which bacteria thrive in your intestines, sometimes reducing the bacterial diversity that supports regular bowel movements
Escalation: The dose is then gradually increased, typically every four weeks, to 0.5 mg, then 1 mg, 1.7 mg (for Wegovy), and finally to a maintenance dose of up to 2 mg (for Ozempic) or 2.4 mg (for Wegovy) once weekly
In the last years, many trials failed to find a unique treatment for all HFpEF phenotypes, apart from sodium-glucose cotransporter 2 inhibitors