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The Incretin Effect The "incretin effect" describes the physiological phenomenon whereby oral glucose administration elicits a much greater insulin response than an equivalent intravenous glucose infusion
A preferred option may not be prescribed
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However, some candidate mechanisms have been proposed, namely, the impairment of AKT translocation through the activation of atypical PKC, and the activation of PP2A [132,133]
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Also, hydrolysis with a range of enzymes is used to release DPP4-inhibitory peptides (Reference Ishikawa, Hira and Inoue69,Reference Lacroix and Li-Chan85Reference Connolly, Piggott and FitzGerald90)
