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Participants were randomly assigned to receive semaglutide alone, semaglutide plus firsocostat, semaglutide plus one of two doses of cilofexor or a combination of all three drugs

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Glucagon-like peptide-1 (GLP-1) receptor agonists are medications approved by the FDA for managing type 2 diabetes and, in some formulations, for chronic weight management

This increases intragastric pressure and can promote reflux of stomach contents into the oesophagus, leading to heartburn and reflux symptoms

Both semaglutide and tirzepatide are administered as a once-weekly subcutaneous injection that you conduct yourself at home

I had certainly felt stuffed at the table before