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This strategy was used for the STEP 1 trial of semaglutide 2.4 mg [38]
Reduced GSH levels shown by decreases in this ratioboth in the plasma and intracellularlyreflect intracellular shifts in oxidative burden and are indicative of immune dysfunction and progression of various disease states such as infection, sepsis, and age-related immune system decline (Guerra et al., 2011
Additionally, we excluded cases with missing data or those lost to follow-up to maintain data completeness
Proc Natl Acad Sci USA (2011) 108:62527
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