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If a 3% reduction in baseline body weight is not observed after 12 weeks, the dosage can be escalated to 11.25/69 mg for an additional 14 days and subsequently increased to 15/92 mg daily
doi: 10.1089/thy.2016.0171 56 GuLYangJGongYMaYYanSHuangYet al
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Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine
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