In 2025, the European Medicines Agency recommended updating semaglutide product information to include NAION as a very rare side effect
The majority of the most common side effects of semaglutide are digestive: gas, belching and bloating, diarrhea, constipation, indigestion, nausea, heartburn, and vomiting
This is why semaglutide was originally developed for type 2 diabetes before its appetite suppression effects were recognized
The key challenge is maintaining adequate nutrition despite reduced appetite
What to look for in a supplier Third-party testing: Reputable suppliers provide certificates of analysis (CoA) from independent labs verifying purity and identity
Taking it first thing in the morning, at least 20 to 30 minutes before breakfast, is a common and effective routine