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The copper ion itself serves as a cofactor for lysyl oxidase, the enzyme responsible for collagen and elastin cross-linking, meaning GHK-Cu both stimulates production of new structural proteins and ensures they are properly stabilized

Similar results were obtained through Oleuropein derivatives from olive fruit extracts, which prevented -synuclein fibrillation and oligomer toxicity 28

The full list of the significantly differentially abundant KOs can be found in Additional file 3, whereas the enrichment analysis of depleted KOs is discussed hereafter