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The number of people without diabetes taking a GLP-1 drug more than tripled between 2018 and 2022 in the U.S., researchers reported March 31 in the Annals of Internal Medicine
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In multiple rodent models of chronic stress (a shared risk factor for major psychiatric illnesses), administration of LAC leads to a rapid and persistent antidepressant-like response by increasing histone acetylation and expression of key genes, including mGlu2 receptors and the downstream brain-derived neurotrophic factor BDNF [27, 30, 34,35,36,37]
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Her assessment considers body mass index, previous weight-loss efforts, health conditions, current medications, and safety factors before an individualized treatment plan is recommended
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