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IGF-1 and survival in ESRD

confirming MOTS-c as a promising mitochondrial-derived peptide with anti-inflammatory and metabolic effects, MOTS-c has been shown to significantly reduce pro-inflammatory markers, improve glucose utilization, and act on fat tissue in ways that make it more directly metabolic than NAD+ in this context

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A cross-talk between metabolic intermediates produced by aerobic glycolysis, and enzymes belonging to the carnitine cycle is also present in cancer cells

The Journal of Physiology, 588 (pt