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The peptide has also been studied in the context of retinal degeneration, where it showed protective effects on retinal pigment epithelium in models of age-related macular degeneration

Neural pathway changes The brain reward circuitry changes in response to weight loss, making calorie-dense foods more rewarding and harder to resist

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It changes how we think about treatment

Clearly the brain/central nervous system effect of these drugs is gaining traction and considerable interest

GHK-Cu also downregulates pro-inflammatory cytokines like TNF-alpha and IL-6, reduces levels of fibrinogen (involved in inflammation), and blocks NF-kB and p38 MAPK activation