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The studies on prevention showed mixed results, though treatment wasn't notably effective

SCFAs improve the suppressive capabilities of Tregs in addition to promoting their differentiation in the gut

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A 6-month Empagliflozin treatment increased FOXP3 expression (compared to baseline) and then improved the protective function of Tregs

The mechanism involves shifting melanin synthesis from darker eumelanin toward lighter pheomelanin and reducing oxidative pigmentation

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