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In turn, activation of macrophages leads to the secretion of interferon- (IFN-), which can downregulate the expression of SLC7A11 and inhibit GSH synthesis, thereby promoting ferroptosis and clearing infected and tumor cells (15)

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It also releases hormones like adrenaline and cortisol, which increase your heart rate and blood pressure, suppress your immune system, and impair your protective skin barrier

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