Additionally, intact glutathione may be absorbed via specific peptide transporters in the small intestine [12][14]
Increased GSH synthesis neutralizes reactive oxygen and nitrogen species and regulates zinc homeostasis promoting neuroprotection after ischemia/reperfusion (162)
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The collapse of both astrocyte and microglia into pro-inflammatory states due to depletion of GSH, leading to sustained neuroinflammation and oxidative stress, is observed in many neurodegenerative diseases (Ferreira et al., 2013
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In a double-blind, placebo-controlled pilot study, Facchin et al