Mol Pharmacol 99:104113 Karhu ST, Vlimki MJ, Jumppanen M, Kinnunen SM, Pohjolainen L, Leigh RS, Auno S, Fldes G, Boije AF, Genns G, Yli-Kauhaluoma J, Ruskoaho H, Talman V (2018.) Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds
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GLP-1 -receptor activation curbs appetite, slows gastric emptying and boosts glucose-dependent insulin release together these cut food intake and steady blood sugar [5] [8]
Epidemiological evidence demonstrates a strong association between obesity and KOA, highlighting shared pathogenic mechanisms
Kennaway DJ et al