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14.4 MOUNJARO Use in Combination with Basal Insulin with or without Metformin in Adult Patients with Type 2 Diabetes Mellitus SURPASS-5 (NCT04039503) was a 40-week double-blind trial that randomized 475 adult patients with type 2 diabetes mellitus with inadequate glycemic control on insulin glargine 100 units/mL, with or without metformin, to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or placebo

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Both compounds were presented once in 24 hours and examined on days 1, 2, 4, 7, and 14

Typically, you may notice improvements in appetite control within two to four weeks, and more significant weight loss after several weeks of consistent use

Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors, studied for obesity and type 2 diabetes

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