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Early viral presence in the lung, along with high rate of lung diseases in PLWH even after ART initiation raise the question on why and how the lung might serve as another anatomical HIV reservoir and what challenges does it pose on our way to a true functional HIV cure
Equally critical is the precise determination of the strain's interaction threshold with intestinal mucin to achieve controlled protective degradation, wherein the mucin-degrading activity must be carefully balanced against its capacity to preserve immune homeostasis
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A double stainless steel guide cannula (26 gauge in diameter, Phymep, France) was implanted into the PVN through stereotactic procedures (A/P: 0.9 mm from bregma, M/L: 0.3 mm and D/V: 4.8 mm from dura mater) as described above
doi: 10.3390/ph18040507 216 BakosBujdos-SzkelyVPatikIKirlyLLangTKozkEet al