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Endocrinology 148:441451 Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A (1993) Mice carrying null mutations of the genes encoding insulin-like growth factor I (igf-1) and type 1 IGF receptor (Igf1r)

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Inflammatory markers like hs-CRP may shift within the first few weeks.

doi: 10.3390/nu16040472 72

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Several inherent factors within tumor cells and the surrounding tumor microenvironment in the body contribute to chemoresistance, as dose suboptimal chemotherapy dosing (Abdullah 2013