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It also attenuates cardiac remodeling by reducing collagen deposition and cardiomyocyte apoptosis, while decreasing the expression of TGF-1 and phosphorylated-Smad3 [171]
The mechanism of action involves binding to GLP-1 receptors located throughout the body, including the pancreas, brain, and cardiovascular system
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While these mechanisms can explain the protective effect that GLP-1 RA exposure had on the fracture risk of the exposed patients in our study, it is important to consider the fact that the findings mentioned were from studies primarily conducted on patients prescribed GLP-1 RA who had a diagnosis of T2DM, as this is what the drugs were originally FDA-approved to treat
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The process itself is quite simple: after connecting a small needle to the body, vitamins and minerals are quickly absorbed directly into the bloodstream
