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Zhai S, Hu X, Hu Y, Wu B, Xing D
Ketamine and psilocybin each produce a brief acute experience but set off a wave of synaptic growth afterward, ketamine through glutamate release and mTOR-dependent synapse formation and psilocybin through rapid, lasting growth of dendritic spines in the frontal cortex, both via BDNF signaling, which is why a single session can shift symptoms for weeks
Baseline hepatic steatosis was assessed by ultrasonography
It is important to note that although DPP-4 inhibition results in a systemic increase in active GLP-1 levels, recent animal data suggest that the glycaemic effects of DPP-4 inhibition might also involve local intestinal inhibition of DPP-4 activity, activation of incretin receptors, reduced liberation of bioactive peptides and increased vagus nerve activity [12]
In the GLP-1 space, there are specific products FDA-approved for diabetes and specific products approved for weight loss
Zipursky JS et al
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