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GH Secretagogue Comparison Compound Class Receptor FDA Status Ipamorelin GHRP (ghrelin mimetic) GHS-R1a Not approved CJC-1295 GHRH analog GHRH-R Not approved Sermorelin GHRH analog GHRH-R Previously approved (Geref, discontinued) Tesamorelin GHRH analog GHRH-R FDA approved (Egrifta) GHRP-2 GHRP (ghrelin mimetic) GHS-R1a Not approved GHRP-6 GHRP (ghrelin mimetic) GHS-R1a Not approved Selectivity Profile: The Key Research Differentiator What makes Ipamorelin stand out among GHRPs is its endocrine selectivity