An alternative and more quantitative approach would be to directly measure PV/BV using the indicator-dilution method, but that would not be practical in a large-scale, international, multicenter randomized trial, leaving us no viable alternatives to explore this potential mechanism
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Capuccio S, Scilletta S, La Rocca F, Miano N, Di Marco M, Bosco G, Di Giacomo Barbagallo F, Scicali R, Piro S, Di Pino A
Zepbound was approved for weight loss by the U.S
This combination of a manageable safety profile and an ethical trial design that prioritizes patient outcomes is encouraging for future clinical adoption and real-world application
But clues of abnormal mitochondria biosynthesis, fusion, fission and mitophagy are well observed in TC [168,169,170,171]