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Tumor-imposed metabolic restrictions can mediate T cell hyporesponsiveness during cancer
Some of these drugs have been approved for the treatment of other diseases, such as simvastatin, everolimus, gefitinib and so on
These findings establish that cysteine is essential for organismal metabolism as removal of cysteine in the host triggers adipose browning and rapid weight loss
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The goal shifts from rapid return to activity toward sustained symptom control and slowing disease progression
