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(2) DPP-4 inhibitors (e.g., sitagliptin, linagliptin),(3) SGLT2 inhibitors (e.g., canagliflozin, dapagliflozin), (4) metformin, and (5) natural supplements such as cinnamon, berberine, and bitter melon

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muciniphila would continue to degrade mucin and produce more SCFAs