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The analysis only included people with obesity or overweight who did not have diabetes because weight loss results in obesity drug trials are typically lower in people with diabetes, making direct comparisons difficult

Take a new needle and remove the outer and inner needle caps

Measures precursor ion mass with high accuracy Confirms molecular weight of GLP-1 peptide Detects mass shifts due to modifications Key Insight: High-resolution MS enables differentiation of closely related peptide species

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