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Semaglutide is a high-purity GLP-1 analogue engineered with a C18 fatty diacid side chain to resist DPP-IV degradation, facilitating a prolonged half-life of approximately 7 days

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It is used as a short-term adjunct to a reduced-calorie diet, exercise, and behavior modification

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High-dose CTX regimens around 200 mg/kg are included in bone marrow transplantation, as escalation to the upper limit significantly reduces the risk of relapse (100)

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