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Individual weight loss on Semaglutide will be dictated by several factors, including adherence to the prescribed treatment schedule, the consistency of dosage escalation, the patients starting weight, and their commitment to accompanying health and lifestyle changes (particularly dietary modification and regular physical activity)
However, more participants discontinued treatment with tirzepatide 10 mg (OR 2.39 [95% CI 1.02, 5.59], I 2 0%) and 15 mg (OR 3.64 [95% CI 1.51, 8.78], I 2 13%) when compared with placebo (ESM Table 3)
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