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To investigate whether VRK2 directly phosphorylates Sec24C, we carried out an in vitro kinase assay and found that overexpression of VRK2 was able to increase the phosphorylation level of Sec24C
De belangrijkste functie is het transporteren van langeketenvetzuren naar de mitochondrin, waar ze worden geoxideerd om energie te produceren ( Pharmacol Res
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J Physiol Paris 87(5):313327
Parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress
