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YL-939, a non-classical ferroptosis inhibitor, has been reported to target prohibitin 2 (PHB2), which suggests binding of YL-939 to PHB2 promotes expression of the iron storage protein ferritin, which reduces iron content and thus susceptibility to ferroptosis
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In this version, an acetyl group is attached to the sulfur atom of the cysteine
There is no good evidence for this, and it is worth being cautious about that framing
doi: 10.1016/j.schres.2014.03.005 186 WangAKMillerBJ