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In vitro applications for Tesamorelin focus on class B GPCR pharmacology at the GHRH receptor, with cAMP-pathway readouts forming the primary functional dataset

For all experiments, data analysis was carried out using library-free analysis mode in DIA-NN

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In Panel A, one can see that the 15 g dose has a relatively small effect on the percentage of surviving hepatocytes in females, descending only from 1 to 0.9