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314,315,316 An increase in peroxisome proliferator activated receptor gamma 2 (PPAR2) and upregulation of hippocampal catalase in KD-fed rats are observed, which may increase anti-inflammatory and antioxidant activity

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However, in the handful of studies that have used NaHCO 3 or citrate in hypoxic conditions, six studies have shown no ergogenic effect [131,132,133,134,135,136], while one study has shown an increase in the anaerobic ( W ) component, which would be suggestive of a performance enhancement, at simulated altitude (14.5% O 2

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