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These data come from Cosmos, a collaboration of Epic health systems representing more than 233 million patient records from 1,325 hospitals and more than 28,900 clinics from all 50 states and Lebanon

Humoral factors in ALS patients during disease progression

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A comprehensive panel of primary antibodies was used to detect various proteins: FOXO4, p53, Ser15-phospho-p53, p21 (cyclin-dependent kinase inhibitor 1A), p16 (cyclin-dependent kinase inhibitor 2A), 3-HSD, CYP11A1, CYP17A1 (cytochrome P450 family 17 subfamily A member 1), and several senescence-associated secretory phenotype (SASP) factors including IL-1, IL-1, IL-6, IL-10, TNF-, and TGF-

These drugs have their drawbacks, though, including cost