Pterostilbene is a dimethylated derivative of RSV with greater bioavailability (Kapetanovic et al., 2011)
The continuous intake of roughage, intensive chewing, and high saliva production (a horse produces 5 to 10 L of saliva per day) is, therefore, essential to protect the stomach mucosa by neutralizing excess gastric acid
There is a higher prevalence of type 2 diabetes mellitus (DT2) in patients with PsO than in the general population.25 In addition, insulin resistance induces dyslipidemia and contributes to the development of nonalcoholic hepatic steatosis (NAHS).26 Cardiovascular risk (CVR) is increased in patients with obesity and PsO who present psoriatic arthritis, and who often have other risk factors.27 The guidelines for the European Cardiology Society state that the body mass index (BMI) should not exceed 25kg/m2,28 and so early interventions to manage obesity or excess weight associated with PsO could contribute to preventing CVR
These drugs are not recommended for people with severe kidney issues or end-stage kidney disease
High oral bioavailability and membrane permeability ensure effective systemic distribution without complex preparation requirements
I use them both daily