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3 In the largest phase 3a trial, STEP 1, results showed that patients taking Wegovy achieved a mean weight loss of 15 per cent (15 kg) sustained over 68 weeks

Here's the honest picture: Strong: Consistent positive results in animal studies Multiple mechanisms that make biological sense Good safety profile in research settings Decades of study without major red flags Weak: Limited human clinical trials Not FDA approved for any indication Long-term effects unknown Quality control issues with commercial products The peptide is stuck in an odd place

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Rather than open access or blanket exclusions, leading employers are tying GLP-1 coverage to objective clinical criteria: BMI thresholds, documented comorbidities, and biometric screening data

"Both the oral tablet and weekly injection formats of Wegovy are approved for helping adults with obesity manage their body weight and lower cardiovascular risk." FDA Approval, December 2025 What false belief prevents people from choosing the right treatment