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It has a genuine FDA-approval history rather than being a novel "research chemical," but no FDA-approved finished product remains on the market, so it is supplied only through compounding pharmacies and prescribed off-label in adults for growth-hormone-axis support, general wellness, or anti-aging purposes rather than its original pediatric indication

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DOI: Published online: March 6, 2023 1 Department of Education, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan 2 College of Medicine, Chang Gung University, Taoyuan, Taiwan 3 Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan 4 Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan 5 Department of Pharmacy, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan 6 School of Pharmacy, Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan 7 MidAtlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA 8 Department of Nephrology, Yang Ming Hospital, Taoyuan, Taiwan 9 Department of Ophthalmology, Jen-Ai Hospital Dali Branch, Taichung, Taiwan Corresponding authors: Eugene Yu-Chuan Kang Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, No

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