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Moreover, loss-of-function mutations of succinate dehydrogenase (SDH) increase cellular succinate level, which inhibits DNA demethylation and contribute to tumorigenesis [62,63]
Biological function GST in metabolite detoxification and antioxidation The classical view holds that as a dimeric isoenzyme, GST can conjugate GSH with substrate molecules in efforts to promote clearance of active ionic substances
Essays Biochem 65(7):885904
Glutathione promotes immune system balance and tolerance, preventing excessive immune activation that can result in allergies, autoimmune diseases, or chronic inflammation
PMID: 62 PangAPuSPanYHuangNLiD
Food allergies: the basics
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