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3.2.1 Impact of metformin on GDM in patients with polycystic ovary syndrome GDM is one of the most common pregnancy complications in patients with PCOS, with significant implications for both the mother and fetus

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250,251 At the same time, ethanol can directly affect the activities of MAT, BHMT, and other enzymes, interfere with Met metabolism, inhibit GSH formation, and weaken the antioxidant capacity of cells