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Glucose is converted via glycolysis to pyruvate, which enters mitochondria and becomes acetylCoA
But, as always happens with big pharma blockbusters, the research community is busy exploring other possible applications for this class of compounds, with clinical trials underway or forming in cardiovascular disease, chronic kidney disease and obstructive sleep apnea
What happened when one patient treated GLP-1 not as a shortcut but as a catalyst My patient, Latha, had Type 2 diabetes and was on daily insulin shots
One study warns that these drugs produce unsustainable volumes of toxic waste and non-degradable solid supports ( [20] ), prompting CDMOs to pursue greener chemistries and solvent-recovery systems (for example, water-based or continuous SPPS) as part of future-capex planning ( [21] ) ( [20] )
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