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The immunomodulatory component of ASHMI that regulates IL-5 and IL-10 production by PBMCs from asthmatic patients were assessed ex vivo , whereby Sophora flacescens fraction 2 (SF-F2) that is alkaloid rich was more effective at increasing IL-10 and fraction 4 (SF-F4) was more effective at decreasing IL-5 [107]
Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, Orskov H
doi: 10.1016/S22138587(22)001875 83 GaoLLeeBWChawlaMKimJHuoLDuLet al
Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases
Reviews in Endocrine & Metabolic Disorders, 23(3), 521539
Fluoxetine is the only antidepressant with FDA approval for bulimia treatment, and it is prescribed at higher doses for this indication than for depression
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