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Dihexa is a synthetic peptide derived from angiotensin IV

Nephroprotective effect of cilastatin against gentamicin-induced renal injury in vitro and in vivo without altering its bactericidal efficiency

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In this BPAM-stabilized state, the LBD clamshells are completely open and show no traces of bound ligands inside the agonist binding pockets and closed channel pore (Figures 7AF)