Oxidative stress plays an essential and complex role throughout its occurrence and progression [2,3,4,5,6], to which reactive oxygen species (ROS) are the primary contributors
This prescription form of B12 is the one most often recommended by healthcare professionals, including primary healthcare services, because it stays in the body for longer, only requiring repeat injection every three months
Paradoxically, this same mechanism may underlie its potential pro-cancer effects: by boosting GSH production, cancer cells can better protect themselves from oxidative damage caused by ROS (Ramachandran and Jaeschke, 2021)
Recently, the obvious senescence phenotypes in keloid lesions and fibroblasts were found and senolytic dasatinib was demonstrated to have antifibrotic effects in keloids 14,15
In addition, its important to maintain realistic expectations and to be patient, as it may take multiple sessions or a combination of treatments to achieve the desired results
Without it, any data collected is fundamentally flawed