Circulating microbial metabolites and immune mediators can access systemic circulation and interact with the bloodbrain barrier (BBB), endothelial cells, and resident immune cells
Engineered butyrate derivatives, tailored bile acid mimetics, and precision dietary treatments aimed at increasing endogenous synthesis of beneficial metabolites are examples of such techniques
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Visualization of the metaphase II meiotic spindle in living human oocytes using the Polscope enables the prediction of embryonic developmental competence after ICSI
Interestingly, they also assessed 1.5% CGN in drinking water in Guinea pigs for 40 days and found no GI lesions, no increase in prostaglandin E2, and a decrease in leukotriene B4