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While acute iron exposure produced minimal biochemical changes and did not sensitize cells to oxidative or ferroptotic challenges, chronic iron exposure induced ferritin upregulation, mitochondrial superoxide accumulation, suppression of GPX4 expression, elevated lipid peroxidation and loss of cellular glutathione (GSH)

Theres reishi , found in a 2023 animal study to promote an enhanced disease-defending [immune] system;59 and chaga , which appears to have anticancer, antioxidant, anti-diabetic, anti-inflammatory, antimicrobial, and immunomodulating properties, per a 2024 review.60 (The blend once contained lions mane , which also has immunoregulatory and antimicrobial qualities, but it has been nixed in the reformulation).61 Thing is, dosing is a problem

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